Several years after Dr. Radford married Elizabeth Campbell Taylor of Pulaski County, Virginia, they purchased from her father 100 acres of land in what is now the City of Radford. There in 1840 the Radfords built on a hill above the New River an impressive brick home and named it "Arnheim" (pictured at right). The house still stands today overlooking the U.S. Route 11 bridge entrance to the city.

In addition to being a practicing physician and successful farmer, the energetic doctor entered into a range of other activities. In 1842 he became the owner for many years of Lovely Mount Tavern located on the heavily traveled Wilderness Road. For a while he was part owner of the Alleghaney Springs Turnpike and in 1860 he invested in the popular Yellow Sulphur Springs resort. Just before his death, he was elected president of an emerging railroad. It is thought by many that it was his generous nature as a private banker that led to the city being named for him.

Dr. and Mrs. Radford and most of their seven children are buried in the family cemetery located near their home "Arnheim".

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